Photo: Thierry Zoccolan/AFP/Getty
A procedure that was hailed for its revolutionary approachleft one person deadand another severely ill last Spring. The doctors involved have now come forward to explain what happened.
In an article published in theNew England Journal of Medicineon Wednesday, a group of doctors from Massachusetts General Hospital detail their mistakes in the fatal fecal microbiota transplantation (FMT), and hope to eliminate some fears about the still-new technology.
“It’s been professionally very challenging,”Dr. Elizabeth L. Hohmann, the lead author of the article, toldThe New York Times. “But this is a cautionary tale about the risks of cutting edge projects.”
The man who died last year was a 73-year-old cancer patient. He and the other patient who fell ill, 69, were reportedly being treated with the same stool in two different experimental trials of FMT — leukemia and liver disease, respectively.
According to theTimes, the doctors say that the stool used to treat the two patients had been contaminated with a strand of E. coli bacteria. Hohmann explained to the outlet that no one had thought to test the material before it was used on the patients.
“It wasn’t obvious to a lot of smart people here,” she told the outlet. “We didn’t think to go back in time.”
After the contaminated stool was transferred to the two men, they both fell ill. The liver patient was treated with powerful antibiotics and was able to recover, but the cancer patient had recently taken drugs to suppress his immune system as part of a bone marrow transplant. He died within 10 days of his last FMT treatment.
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Next week, the agencyplans to hold a public hearingin Washington D.C. to discuss the risks and benefits of the procedure.
source: people.com
